Safety and effectiveness of longer‐term phentermine use: Clinical outcomes from an electronic health record cohort. Safety assessment of combination therapies in the treatment of obesity: Focus on naltrexone/bupropion extended release and phentermine-topiramate extended release. Adipex-p (phentermine hydrochloride) capsules label.You can learn more about how we ensure our content is accurate and current by reading our editorial policy. We link primary sources - including studies, scientific references, and statistics - within each article and also list them in the resources section at the bottom of our articles. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Health insurance may also help cover costs in some cases.

It is also not advisable to take the drug in the evening or at night, as this may cause insomnia.ĭifferent forms and dosages of phentermine will vary in price. Children under 16 years should also avoid the drug, due to uncertain risks. Others with late-stage kidney disease may not be able to take the drug.ĭoctors do not recommend phentermine in older adults, as it may stress the kidneys. People with impaired kidneys may require smaller doses to avoid additional stress on these organs. Some underlying conditions will also change dosage recommendations. Typical doses of phentermine for adults contain 15 milligrams (mg), 30 mg, or 37.5 mg, which delivers 12 mg, 24 mg, 30 mg of phentermine, respectively.Ī daily dose of phentermine and topiramate can vary from 3.75 mg phentermine and 23 mg topiramate, to 15 mg phentermine and 92 mg topiramate. Doctors may tailor the amount to ensure a person takes the minimum effective dose.

Phentermine, or a medicine that contains a mix of phentermine and other drugs, typically comes in an oral capsule. OverdoseĪ person who takes too much phentermine may overdose. Talk to a doctor about the risk of withdrawal in each case. People who take prolonged doses may also experience withdrawal symptoms when they stop the drug. In these cases, it is important to discontinue phentermine altogether, and move on to other methods to lose weight. Some people may become tolerant to the drug, and want more to feel the same effects. As such, there is potential for abuse and dependence when someone takes phentermine. Phentermine is chemically related to amphetamine drugs, such as methamphetamine, a stimulant with a history of abuse. Phentermine could also interact with alcohol, so a person on the drug should try to avoid alcoholic drinks. They may need to reduce their insulin or other medications when they take the drug. Pregnant or breastfeeding women should also avoid phentermine until they stop breastfeeding.ĭoctors will monitor people with diabetes or hypoglycemia who take phentermine.

using antidepressants, such as monoamine oxidase inhibitors or selective serotonin reuptake inhibitors.

Other conditions or medicationsĪ person’s conditions or medications may mean phentermine is unsuitable for them as a weight loss drug. Doctors recommend that people take time away from work when they first start the drug, to gauge any side effects.

In some cases, these drugs may also make someone unable to drive or operate heavy machinery. Phentermine alone or in combination with other drugs, such as topiramate, may have their own risk of side effects, including: There are risks with phentermine, and a doctor will discuss them before they prescribe the drug for weight loss.

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